Dermal Fillers, Skin Boosters, and Biostimulators: Exploring the Differences

Cosmetic skin treatments have evolved to provide various options for rejuvenating the skin and combating the signs of aging. Dermal fillers, skin boosters, and biostimulators are popular choices, each with its unique properties and purposes.

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Dermal Fillers:

  • Composition: Dermal fillers are typically made from substances like hyaluronic acid (HA) or calcium hydroxylapatite (CaHA), known for their skin-plumping properties.
  • Purpose: Dermal fillers are primarily used to address wrinkles, fine lines, and areas with volume loss. They can enhance lips, and cheeks, and correct deep lines and hollow areas.
  • Mechanism: Fillers work by physically adding volume to treated areas, resulting in immediate, smoother skin.

Skin Boosters (Polynucleotides):

  • Composition: Skin boosters like Rejuran often contain polynucleotides, which improve skin health quality , and stimulate collagen production in some extend.
  • Purpose: These treatments enhance skin texture, hydration, and overall quality. They subtly rejuvenate the skin and address issues like fine lines and dullness.
  • Mechanism: Hydrate the skin from within and have cell-healing properties with anti-inflammatory effects.

Biostimulators / (Collagen Stimulator)

  • Composition: Biostimulators like Profhilo contain hyaluronic acid but have a unique structure that spreads throughout the skin.
  • Purpose: They improve overall skin quality, address skin laxity, and provide a natural-looking lift to the face, often used for anti-aging purposes.
  • Mechanism: These products stimulate collagen and elastin production, promoting long-term rejuvenation.

Notable Products:

  • Dermal Fillers: Juvederm, Restylane, Radiesse, Hyabell
  • Skin Boosters: Rejuran, Diamond Feel Forte
  • Biostimulators: Profhilo, Sculptra, Ellanse


1) Dermal fillers add immediate volume to specific areas.

2) Skin boosters enhance skin texture, cell repair, and hydration gradually.

3) Biostimulators promote collagen production for overall rejuvenation.

  • The choice depends on individual goals and skin conditions.
  • Always consult with a qualified practitioner for the most suitable treatment.

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