AK Combi targets the ACNE causing factors from inside out.
The synergistic combination of Epigallocatechin gallate and Zinc gluconate targets the pathogenesis of acne and counteracts the effect of IGF-1 (Insuline-Similar Growth Factor).
Bolstered with niacin, to improve overall skin health and skin barrier function to prevent bacterial activity on the skin.
Food supplement based on a combination of Epigallocatechin Gallate (antioxidant, extract from green tea), vitamin B3 (niacin), and zinc (zinc gluconate), which reduces inflammation and contributes to the maintenance of normal skin and to the protection of cells from oxidative stress.
THE ROLE OF IGF-1 in the pathogenesis of acne
What is it?
IGF-1 (Insulin-like Growth Factor) is a protein hormone
produced by the liver in correlation with the levels of GH (Growth Hormone).
By what is it induced?
The synthesis of IGF-1 is also promoted by the consumption of
food with a high glycemic charge (pasta, etc...), milk and derivatives (Western diet).
How does it act?
IGF-1 links with its receptor (IGF-1R), expressed at the level of
keratinocytes and sebocytes, stimulating their proliferation.