What is Novuma biostimulator treatment?
Novuma is an injectable calcium hydroxylapatite (CaHA) biostimulator that may support facial firmness, density and gradual collagen regeneration. Manufactured by Laboratoires Vivacy, Novuma uses smooth, round CaHA microspheres in a carboxymethyl cellulose gel carrier, and is CE-marked (CE 2292) and registered with the Medical Device Authority (MDA) Malaysia.
Novuma is different from a simple dermal filler. It does not mainly work by adding volume. Instead, the CaHA microspheres act as a scaffold that signals your own fibroblasts to produce new collagen over time, while the gel carrier may provide an earlier lifting effect depending on how the product is placed.
At Klinik Dr Diana, the first step is not choosing the product name. The first step is checking whether your concern is firmness loss, skin density, facial contour, texture, hydration, acne scars, pigmentation or a combination of issues.
Book a consultation at Klinik Dr Diana to check whether Novuma is suitable for your firmness, density or skin-quality goals.
WhatsApp UsWhat you need to know
Novuma can be helpful when the goal matches what CaHA biostimulation can realistically do: restore firmness, improve skin density and stimulate gradual collagen regeneration. It is not suitable for every skin concern and should not be chosen without assessment.
- Novuma is made of calcium hydroxylapatite (CaHA) microspheres, concentrated at 55–60% in a carboxymethyl cellulose gel carrier.
- It uses Vivacy’s Advanced BioSphere Technology, with smooth, round particles designed for consistent biostimulation.
- Some lifting effect may be seen early, while collagen-related changes develop gradually over months.
- It is not a hydration booster and is not primarily for pigmentation or active acne.
- It is not dissolved with hyaluronidase like many hyaluronic acid fillers.
- Correct placement, patient selection and injector experience are important for safety.
Why is Novuma called a next-generation biostimulator?
Novuma is described as a next-generation biostimulator because its CaHA microspheres are engineered to be smooth and round for consistent collagen stimulation with controlled inflammation. This mechanism may support firmness, elasticity and skin structure in suitable patients.
This is different from a standard filler-only effect. A typical filler adds volume by occupying space. A biostimulator like Novuma also aims to improve the tissue environment gradually by encouraging fibroblasts to build new collagen.
The word “stimulator” should still be understood carefully. It describes the mechanism, not a guarantee. Results vary depending on skin quality, age, placement, technique and biological response.
What can Novuma help with?
Novuma may be considered for selected concerns involving facial firmness, density, contour softening and skin quality. Whether it is appropriate depends on the area, anatomy and treatment goal.
- Cheek firmness and softened mid-face contour
- Nasolabial folds in selected patients
- Marionette lines running from the corners of the mouth downward
- Jawline definition and lower-face support in suitable anatomy
- Skin firmness and density in patients with early laxity
- Overall skin quality improvement through gradual collagen regeneration
- Patients who prefer gradual, natural-looking collagen-supporting treatment rather than volume alone
Novuma may be considered for selected facial areas including the cheeks, nasolabial folds, marionette lines and jawline, depending on individual assessment.
The CaHA microspheres in Novuma act as a scaffold that stimulates fibroblasts, leading to gradual collagen regeneration and improved skin quality over months.
Novuma is not usually the first choice for hydration-only concerns, active acne, melasma, pigmentation or true acne-scar tethering. Those concerns may need different treatments.
How does Novuma work?
Novuma works through a dual mechanism: an early lifting effect from the gel carrier and a gradual biostimulatory effect from CaHA microspheres. Over time, the microspheres are gradually broken down and absorbed by the body, leaving behind a newly built collagen network that continues to support the skin.
How Novuma behaves depends on technique. When placed structurally, it may support contour and lift. Across a broader treatment plan, it is used to encourage collagen remodelling for firmness and skin quality.
Novuma uses smooth, round CaHA microspheres suspended in a carboxymethyl cellulose gel carrier, designed for consistent collagen stimulation.
1. Consultation and facial assessment
The doctor checks whether your concern is related to firmness, density, contour, texture, laxity or hydration. Previous fillers, biostimulators, facial procedures, medical history and risk factors should be reviewed before planning treatment.
2. Treatment planning and marking
The doctor decides whether Novuma is appropriate, which areas to treat, and whether the technique should focus on structural support, biostimulation for firmness, or a combination approach with other treatments.
3. Novuma injection
The injection method depends on the treatment area and goal. A needle or cannula may be used. Comfort measures may be applied, and injection should be performed with careful anatomical awareness.
4. Review and aftercare
After treatment, mild swelling, bruising, tenderness or injection marks may occur. You will receive aftercare guidance and instructions on when to contact the clinic if anything feels unusual.
Novuma at a glance
| Feature | Detail |
|---|---|
| Product type | Injectable CaHA biostimulator |
| Active ingredient | Calcium hydroxylapatite 55–60% in CMC gel |
| Manufacturer | Laboratoires Vivacy (France) |
| Regulatory status | CE-marked (CE 2292) · MDA Malaysia registered |
| Session time | ~ 30–45 minutes |
| Downtime | Usually minimal — mild swelling or bruising 1–3 days |
| Onset of results | Early lifting effect + progressive collagen response over weeks to months |
| Reversible? | No — not dissolved by hyaluronidase |
Who may be suitable for Novuma?
Novuma may suit selected adults who are experiencing loss of firmness, softened facial contour or reduced skin density, and who want a gradual, collagen-supporting approach rather than volume-only treatment. It is not a one-size-fits-all injectable.
Novuma may be considered for patients who understand that the treatment must be planned according to anatomy and that collagen-related changes take time. Patients who want hydration only, very soft lip enhancement, tear-trough correction, active acne care or pigmentation treatment may need different options.
Who may not be suitable?
Novuma may not be suitable for patients who are pregnant or breastfeeding, have active infection or inflammation in the treatment area, have certain allergies or medical conditions, or have a treatment goal that would be safer or more appropriate with another product.
It may also be unsuitable when a patient wants a reversible hyaluronic acid filler, a hydration booster, or a treatment for concerns Novuma does not primarily address.
What results can you realistically expect?
Novuma results depend on how it is used. Structural use may show an earlier lifting effect, while collagen-related firmness and skin-quality benefits develop gradually over weeks to months.
Results are not permanent and cannot be guaranteed. Maintenance depends on the treated area, amount used, technique, metabolism, lifestyle and how your tissue responds.
A realistic results timeline
| Timing | What may happen |
|---|---|
| Immediately after | An early lifting or smoothing effect may be visible depending on technique. Swelling should not be judged as the final result. |
| First few days | Bruising, tenderness, injection marks or mild swelling may appear and usually settle gradually. |
| Following weeks | Collagen-related firming and skin-quality changes may begin to develop. |
| Over months | The collagen-stimulating effect becomes easier to evaluate. Review timing should be personalised. |
Novuma vs hyaluronic acid filler
| Feature | Novuma | Hyaluronic acid filler |
|---|---|---|
| Main material | Calcium hydroxylapatite microspheres in a gel carrier | Hyaluronic acid gel |
| Main role | Collagen stimulation and firmness support | Volume, contour or hydration depending on product type |
| Collagen stimulation | Yes, this is the primary mechanism | Usually not the main mechanism |
| Reversibility | Not dissolved with hyaluronidase | Many HA fillers can be dissolved with hyaluronidase |
| Best choice depends on | Anatomy, firmness goals, density needs and safety assessment | Anatomy, area, desired softness, reversibility and treatment goal |
What are the possible side effects?
Common short-term effects may include swelling, bruising, redness, tenderness, itching, injection marks or temporary firmness. Lumps or nodules can occur, especially if product placement, technique or aftercare is not suitable.
Rare but serious biostimulator-related complications can include infection, vascular compromise, skin injury, scarring or vision-related complications. Seek urgent medical attention if you develop severe pain, skin colour changes, blistering, worsening swelling, visual symptoms or symptoms that feel unusual after injection.
What should you do before and after Novuma?
| Before treatment | After treatment |
|---|---|
| Tell the doctor about previous fillers, biostimulators and aesthetic procedures. | Follow the clinic’s aftercare instructions closely. |
| Share medications, blood thinners, allergies and medical conditions. | Avoid pressing or massaging the area unless instructed. |
| Inform the clinic if you are pregnant, breastfeeding or unwell. | Expect possible bruising, swelling or tenderness. |
| Discuss whether you prefer a reversible option. | Contact the clinic urgently for severe pain, skin colour change or visual symptoms. |
Why consider Klinik Dr Diana for Novuma?
Klinik Dr Diana uses an assessment-first approach before recommending Novuma. The aim is to identify whether your concern is firmness, density, collagen support, hydration, volume loss or another issue before choosing an injectable.
For patients in Bandar Baru Bangi, Senawang, Seremban, Putrajaya, Kajang and nearby areas, this helps reduce the risk of choosing a product that does not match the real concern.
- Doctor-supervised injectable treatment planning
- Assessment of facial anatomy, skin quality and treatment goals
- Clear explanation of Novuma as a biostimulator, not just a filler
- Realistic expectations about gradual collagen response
- Safety discussion, aftercare and review pathway
Not sure whether you need Novuma, another biostimulator, HA filler, skin booster or an energy-based treatment? A consultation can help identify the right starting point.
Book an AssessmentHow much does Novuma cost?
Novuma pricing may vary depending on treatment area, amount used, technique, branch availability and whether it is combined with other treatments. Please contact Klinik Dr Diana for current pricing after assessment.
Ask Klinik Dr Diana about Novuma suitability, pricing and branch availability.
WhatsApp UsReferences
- Amiri M, Meçani R, Niehot CD, et al. Skin regeneration-related mechanisms of calcium hydroxylapatite (CaHA): a systematic review. Journal of Cosmetic Dermatology. 2024;23(1):7–19.
- Amiri M, Meçani R, Llanaj E, et al. Calcium hydroxylapatite and aesthetic outcomes: a systematic review of controlled clinical trials. Journal of Clinical Medicine. 2024;13(5):1686.
- Hong JY, Park KY. Dual benefits of calcium hydroxyapatite filler: a prospective study on midface volume restoration and skin quality enhancement. Journal of Cosmetic Dermatology. 2025.
- Zago Sá Fortes R, Cassol Spanemberg J, Cherubini K, Salum FG. Adverse events and satisfaction outcomes with calcium hydroxylapatite and polycaprolactone fillers in facial aesthetics: a systematic review. Cosmetics. 2024;11:165.
- Beleznay K, Carruthers JDA, Humphrey S, Jones D. Avoiding and treating blindness from fillers: a review of the world literature. Dermatologic Surgery. 2015;41(10):1097-1117.
- Laboratoires Vivacy. Novuma Instructions for Use. Used for neutral product and safety information, not as a guarantee of results.
The references above support general CaHA biostimulator concepts. Individual suitability must still be assessed in person.
Frequently asked questions about Novuma
The most common questions about Novuma are answered below. Because Novuma is a biostimulator with gradual collagen effects, an in-person consultation is recommended before deciding whether it suits your concern.
Possible side effects
Possible effects include swelling, bruising, redness, tenderness, itching, firmness, temporary lumps, nodules, infection or asymmetry. Rare but serious biostimulator-related complications such as vascular compromise, skin injury or vision-related complications require urgent medical attention.
Individual results vary according to age, anatomy, skin quality, treatment area, product placement, technique, medical history and biological response. Novuma is not suitable for everyone and is not reversible in the same way as hyaluronic acid filler. This page is for general educational information and does not replace medical consultation.
Want to understand whether Novuma suits your firmness, density or skin-quality concerns? Book an assessment at Bangi or Senawang.
WhatsApp UsFrequently asked questions
What is Novuma?
Novuma is an injectable calcium hydroxylapatite (CaHA) biostimulator manufactured by Laboratoires Vivacy. It is designed to stimulate the skin's own collagen production and may support facial firmness, density and skin quality in suitable patients.
Is Novuma the same as Radiesse?
Both Novuma and Radiesse are CaHA-based biostimulators but they are different products manufactured by different companies with different particle technology and gel carriers. During consultation, the doctor will explain why a specific product may be considered for your case.
Is Novuma registered in Malaysia?
Yes. Novuma is CE-marked (CE 2292) as a Class III medical device and is registered with the Medical Device Authority (MDA) Malaysia.
What areas can Novuma treat?
Novuma may be considered for selected facial areas such as the cheeks, nasolabial folds, marionette lines and jawline or oval of the face. Suitability depends on facial anatomy, skin quality and treatment goals.
How does Novuma work?
Novuma works through a dual mechanism. The gel carrier may provide an early lifting effect, while the CaHA microspheres act as a scaffold that encourages fibroblasts to produce new collagen gradually over weeks to months.
When will I see results after Novuma?
Some early lifting or smoothing effect may be visible on the day of treatment. Collagen-related firmness and skin-quality changes usually develop gradually over the following weeks to months.
How long do Novuma results last?
Duration varies depending on age, skin quality, lifestyle, treated area, technique and biological response. Published literature on CaHA biostimulators generally reports outcomes lasting several months to over a year, but this cannot be guaranteed.
How many sessions of Novuma do I need?
Most patients start with one to two sessions spaced a few weeks apart, but the exact plan depends on baseline skin quality, degree of firmness loss and treatment goals. The plan is confirmed after in-person assessment.
Is Novuma safe?
Novuma is a CE-marked, MDA-registered medical device with published clinical data. However, it is still an injectable procedure with risks such as bruising, swelling, nodules, infection and rare vascular complications. Suitability and technique matter.
Is Novuma reversible?
Novuma is not dissolved with hyaluronidase like many hyaluronic acid fillers. This is why careful assessment, correct placement and conservative planning are important.
Who should avoid Novuma?
Novuma may be unsuitable during pregnancy or breastfeeding, with active infection or inflammation in the treatment area, certain allergies, some medical conditions or when the treatment goal does not match what a biostimulator can safely achieve.
How much does Novuma cost at Klinik Dr Diana?
Pricing may vary by treatment area, amount used, technique, branch availability and whether it is combined with other treatments. Please contact Klinik Dr Diana for current pricing after assessment.
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